HOSPITAL OVERALL DISINFECTION SOLUTION SERVICE PROVIDER

Disinfection mechanism and characteristics of o-phthalaldehyde disinfectant


Release time:

2021-11-02

Phthalaldehyde, is an important pharmaceutical and chemical intermediates, previously mainly used for amine alkaloids, histamine fluorometer reagents and pharmaceutical testing. Since it was used for endoscopic disinfection in 1994 and found that it has a good disinfection effect, many studies have been carried out on the disinfection of o-phthalaldehyde abroad, and it has been developed into a new type of efficient disinfectant and passed the US FDA certification. Compared with the disinfectant glutaraldehyde (GTA), o-phthalaldehyde has the advantages of broad-spectrum, high efficiency and low corrosion, and also has its own characteristics of low irritation and low use concentration. In addition, o-phthalaldehyde also has a good killing effect on glutaraldehyde-resistant mycobacteria isolated in recent years. Therefore, o-phthalaldehyde has the potential to be a substitute for glutaraldehyde.

Ortho-phthalaldehyde (OPA) is a new type of high level disinfectant, which has the characteristics of low toxicity, low irritation to human skin and strong ability to kill microorganisms. in 1999Year 10It was widely accepted by hospitals soon after it was approved by the US FDA in January. OPA is a light blue pHValue 7.5The liquid, OPA solution (0.55%) is effective at room temperature, with high efficiency in killing Mycobacterium tuberculosis and high level disinfection ability. It can quickly and effectively disinfect various instruments and endoscopes. It is compatible with many materials, including metals, plastics, artificial rubber bodies and adhesives commonly used in reusable medical devices.

Phthalaldehyde, is an important pharmaceutical and chemical intermediates, previously mainly used for amine alkaloids, histamine fluorometer reagents and pharmaceutical testing. Since it was used for endoscopic disinfection in 1994 and found that it has a good disinfection effect, many studies have been carried out on the disinfection of o-phthalaldehyde abroad, and it has been developed into a new type of efficient disinfectant and passed the US FDA certification. Compared with the disinfectant glutaraldehyde (GTA), o-phthalaldehyde has the advantages of broad-spectrum, high efficiency and low corrosion, and also has its own characteristics of low irritation and low use concentration. In addition, o-phthalaldehyde also has a good killing effect on glutaraldehyde-resistant mycobacteria isolated in recent years. Therefore, o-phthalaldehyde has the potential to be a substitute for glutaraldehyde.

Phthalaldehyde has good stability in the range of pH 3-9, and its solution can be used continuously for 14 days. The US company iCdxe has developed a test strip for accurate concentration monitoring. It has been shown that if an automated endoscopic cleaning procedure is used, it can be used 82 times before reaching the minimum effective concentration, while glutaraldehyde can be used only 40 times. o-phthalaldehyde is not harmful to many metals, plastics and other substances

The advantages of ANNJET ansett o-phthalaldehyde disinfectant:
① Ultra-low concentration, the concentration of dimethyl aldehyde is 0.5-0.6, only 1/4 of glutaraldehyde disinfectant
② efficient disinfection, 5 minutes of high-level disinfection (machine wash),90 minutes to kill spores, no drug-resistant bacteria, mycobacteria and other aldehydes disinfection resistant bacteria can be efficiently killed.
No carcinogenic, teratogenic and other toxic effects, no irritation, no respiratory system and nervous system toxicity.
④ Non-corrosive to metal instruments



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