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近年来，伴随着临床医疗技术的完善和发展，具有操作 简单、创伤小等临床优势的内镜技术被广泛用于临床疾病检 查和治疗中，取得显著效果。然由于此类技术临床费用高 , 且直接和患者器官接触，一旦使用前期消毒处理不彻底，将 降低临床效果，甚至危及患者生命安全[1]。因此，如何提高 内镜消毒效果、降低临床使用成本成为目前急需解决的主要 问题。为更好地探讨内镜消毒效果，本研究将我院行邻苯二 甲醛、戊二醛消毒处理内镜作为主要调查对象，研究邻苯二 甲醛、戊二醛在内镜消毒中的临床应用效果。

1 Data and Methods 1.1 General Data 80 cases of endoscopes after endoscopy in our hospital from September 2001 to March 2005 were taken as the research objects and divided into different disinfection treatment groups, 40 cases of patients in group A, date of receipt: 2016 -05 -04, 21 cases of males and 19 cases of females; Age 15~79 years old, the average age was (45.5±2. 5) years old. Among them, there were m patients examined by gastroscope (model 260Z) and 16 patients examined by colonoscopy (model 260A Z I). There were 40 patients in group B, 22 males and 18 females. Age 16~80 years old, average (45.6±2.6) years old; Among them, 25 patients were examined by gastroscope (model 260Z), colonoscopy (model 260A Z I) examined 15 patients. The differences in general data such as gender, age, and endoscopic model used in the two groups of endoscopy patients were not statistically significant (P. 0.05) and were comparable. 1.2 method clinical endoscope disinfection treatment adopts artificial disinfection method, which is operated in strict accordance with the relevant requirements of the technical operation specification for endoscope cleaning and disinfection issued by the health department. after the endoscope is used, the surface dirt will be removed with the help of moist gauze immediately, and water and air will be delivered repeatedly for 10 s, then the waterproof cap of the endoscope will be covered in a common container and sent to the disinfection room for disinfection, the endoscope shall be disinfected according to the steps of water washing, acylation washing, cleaning, disinfection and flushing. When the steps are switched, the water contained in the endoscope will be sucked dry, and the water on the surface of the endoscope will be dried at the same time. Then, the endoscope after disinfection and drying was placed in phthalaldehyde and glutaraldehyde disinfection tanks respectively, 5 m m m in phthalaldehyde disinfection tank and 10 m m m in glutaraldehyde disinfection tank, and the resistant bacteria could be extended to 30~45 m m. Clinical endoscopic disinfection after sampling processing, easy to evaluate the disinfection effect, method:(1) cavity sampling. After endoscope disinfection is completed, 10.0 m l of 0.9 sodium chloride injection will be injected inward with a sterile syringe, which will be mainly injected into the endoscopic cavity biopsy population, then withdrawn from the biopsy outlet and sent to the clinical laboratory for examination within 2 hours. (2) surface sampling. Wiping the endoscope with cotton swabs shows that the cotton wool above the cotton swab is put into a sterile test tube and sent for inspection within 2 h. 1.3 Evaluation Project After the end of the clinical endoscopic sampling test, the disinfection effect was evaluated, and the clinical work efficiency and disinfection time of the two groups of disinfectants were recorded in detail. Standard for disinfection effect of endoscopes: if the residual bacterial colonies of endoscopes after disinfection are below 20 c f per piece, no growth of pathogenic bacteria indicates that disinfection is qualified. 1.4 statistical methods apply S P S 18. 0 software for the research and analysis of relevant data, measurement data comparison using the "test, counting data comparison using the test. 05 is statistically significant for the difference.

2 结果 2 . 1 临床内镜消毒效果评定 两组内镜消毒处理后合格率均为 100. 〇% , 差异无统计 学 意 义 （P >0.05)。

2 . 2 临床工作效能及消毒时间指标评定 A 组内镜消毒时间为5 m i n , B 组内镜消毒时间为 10 m i n , 两组临床消毒时间差异有统计学意义（P <〇.〇5);且两组内镜预约时间、消毒总量等工作效能指标差异有统计学意义（P <〇.〇5)。

3 Discussion Clinical endoscopy is a kind of human and minimally invasive disease diagnosis equipment, which is widely used in clinical disease diagnosis and treatment with its clinical advantages of small trauma and simple operation. However, due to the special material and complex structure of endoscopic equipment, it indirectly increases the difficulty of disinfection treatment after clinical use. Once the endoscope is not completely disinfected, it will directly affect the safety of patients. At present, the commonly used clinical disinfectant is glutaraldehyde, but this kind of disinfectant itself has great toxicity, coupled with the influence of improper use and other factors, it is easy to endanger the health of patients and medical staff. Moreover, the use time of clinical glutaraldehyde disinfectant is relatively long, 10~40 m m, which affects the repeated use of endoscopy, reduces the compliance of endoscopy disinfection of medical staff, and increases the rate of hospital cross infection. Therefore, the clinical need to choose a reasonable and effective disinfectant for disinfection. In recent years, our hospital has found through continuous research that phthalaldehyde disinfectant has obvious effect. although there is no significant difference between the qualified rate of clinical disinfection rate and glutaraldehyde disinfectant, there is significant difference between the two groups in disinfection use time (p <0.05), which shows that clinical phthalaldehyde disinfectant can improve the frequency of endoscopic use, improve the working effect of endoscopic operators, and facilitate the overall work quality of the hospital [2]. Ou Yanni et al. [3] studies have shown that o-phthalaldehyde is a new clinical disinfectant with the clinical advantages of strong sterilization, strong stability, simple preparation and short operation time. Moreover, such disinfectants will not produce clinical stimulation to operators, and there is no need for activation treatment and relatively special ventilation settings during use. As a result, phthalaldehyde disinfectants are used in endoscopic disinfection in most countries. Our hospital has also confirmed the disinfection effect of phthalaldehyde through clinical research, but it should be emphasized that thorough cleaning and flushing are required in the early stage of endoscopic disinfection treatment. Only in this way can the disinfection effect be guaranteed. At the same time, because the phthalaldehyde disinfectant is prone to gray reaction after contact with clothing and skin, which increases the difficulty of cleaning, it is necessary to strengthen its own skin protection during the use of the disinfectant to minimize the spraying of the disinfectant. At present, most hospitals in China use traditional glutaraldehyde disinfectant to disinfect endoscopic equipment. Although it is safe and reliable, the disinfection time is long, so that patients cannot wait for a long time. The results of this study showed that the clinical pass rate of 100.0 percent was obtained after the clinical disinfection of endoscopes by phthalic aldehyde disinfectant and glutaraldehyde disinfectant, indicating that the clinical disinfection effect of the two disinfectants was significant, and the difference was statistically significant compared with the clinical work efficiency of phthalic aldehyde disinfectant and glutaraldehyde (P. 0.05). Conclusion: The clinical use of phthalaldehyde to disinfect endoscopes has a significant effect, which can shorten the disinfection time and reduce toxicity, and is worth using. [References] [ 1] Zhou Xiaoliang, Li Wen. Comparative study on disinfection of digestive endoscopy with o-phthalaldehyde and glutaraldehyde [J ] . Chinese Journal of Microecology, 2013, 25 (4): 454-45 6 . [ 2] Lin Jiang, Gao Shan, Xu Haili, et al. Comparison of disinfection effect and durability of o-phthalaldehyde, glutaraldehyde and chlorine-containing disinfectants on endoscopes [J ] . Journal of Nurses Education, 2013, 28 (I5 ):1414-1415.[3] Ou Yanni, Liang Zulan, Ye Wanhua, etc. Observation of the effect of phthalaldehyde on endoscopic disinfection [J]. Modern Clinical Nursing, 2012, 11 ( 1 ) : 31 -32.